| # | Player | Team | Apps | Top scorers |
|---|---|---|---|---|
| 1 |  D. Arcila |  Leon | 6 | 4 |
| 2 |  M. Uzuni |  Austin | 4 | 4 |
| 3 |  B. Rodríguez |  Club America | 6 | 3 |
| 4 |  D. Cambindo | Leon | 5 | 3 |
| 5 |  F. Viñas |  Toluca | 6 | 3 |
| 6 |  H. Cuypers |  Monterrey | 6 | 3 |
| 7 |  A. Lassiter |  Portland Timbers | 3 | 3 |
| 8 |  Helinho | Toluca | 6 | 3 (1) |
| 9 |  D. Rossi | Monterrey | 6 | 2 |
| 10 |  Brais Méndez |  Columbus Crew | 4 | 2 |
| 11 |  E. Bullaude |  Santos Laguna | 3 | 2 |
| 12 |  J. Pereyra |  Minnesota United FC | 3 | 2 |
| 13 |  J. Paradela |  Cruz Azul | 3 | 2 |
| 14 |  Evander |  FC Cincinnati | 3 | 2 |
| 15 |  L. Messi |  Inter Miami | 2 | 2 |
| 16 |  I. Violante | Club America | 6 | 2 |
| 17 |  O. Pineda | Monterrey | 5 | 2 |
| 18 |  S. Solans |  Real Salt Lake | 4 | 2 |
| 19 |  P. Ruiz | Real Salt Lake | 4 | 2 |
| 20 |  P. Dithejane |  Chicago Fire | 4 | 2 |
| # | Player | Team | Apps | Assists |
|---|---|---|---|---|
| 1 | B. Rodríguez | Club America | 6 | 3 |
| 2 |  Raphael Veiga | Club America | 6 | 3 |
| 3 |  L. Ocampos | Monterrey | 6 | 3 |
| 4 |  N. Allen | Inter Miami | 3 | 3 |
| 5 | D. Cambindo | Leon | 5 | 2 |
| 6 |  David Pereira da Costa | Portland Timbers | 3 | 2 |
| 7 |  M. Guilavogui | Real Salt Lake | 4 | 2 |
| 8 |  T. Spicer |  Orlando City SC | 2 | 2 |
| 9 |  I. Moreno | Leon | 6 | 2 |
| 10 |  D. Luna | Real Salt Lake | 4 | 2 |
| 11 |  T. Habroune | Columbus Crew | 4 | 2 |
| 12 |  A. Salétros | Chicago Fire | 4 | 2 |
| 13 |  Bryan Josías Ramírez León | FC Cincinnati | 3 | 2 |
| 14 |  E. Echenique | FC Cincinnati | 3 | 2 |
| 15 |  P. Rothrock |  Seattle Sounders | 3 | 2 |
| 16 |  J. Torres |  FC Juarez | 3 | 2 |
| 17 |  Marcus Caldeira | Minnesota United FC | 2 | 2 |
| 18 |  F. Beltrán | Leon | 0 | 2 |
| 19 | D. Arcila | Leon | 6 | 1 |
| 20 | M. Uzuni | Austin | 4 | 1 |
| # | Player | Team | Apps | Yellow cards |
|---|---|---|---|---|
| 1 |  J. Romaña | Leon | 5 | 3 |
| 2 |  A. Cervantes | Club America | 6 | 3 |
| 3 |  Juan José Guevara Possu | Leon | 6 | 3 |
| 4 |  F. Pereira | Toluca | 6 | 3 |
| 5 |  J. Rodríguez | Monterrey | 4 | 3 |
| 6 |  W. Cartagena | Orlando City SC | 3 | 3 |
| 7 |  R. Juárez | Club America | 3 | 3 |
| 8 |  S. Barreto |  CF Pachuca | 2 | 2 |
| 9 |  É. Sánchez | Club America | 6 | 2 |
| 10 |  S. Vegas | Leon | 6 | 2 |
| 11 | L. Ocampos | Monterrey | 6 | 2 |
| 12 | D. Arcila | Leon | 6 | 2 |
| 13 |  B. Šabović | Austin | 4 | 2 |
| 14 |  O. Svatok | Austin | 4 | 2 |
| 15 |  S. Mariscal | Santos Laguna | 3 | 2 |
| 16 |  Paulo Ramírez |  Atlas | 3 | 2 |
| 17 |  S. Sanabria |  Puebla | 3 | 2 |
| 18 |  K. Velde | Portland Timbers | 3 | 2 |
| 19 |  D. Martínez |  Los Angeles FC | 3 | 2 |
| 20 |  O. Urhoghide |  FC Dallas | 3 | 2 |
| # | Player | Team | Apps | Red cards |
|---|---|---|---|---|
| 1 |  J. Rosales | Austin | 4 | 1 |
| 2 |  Ilie Sánchez | Austin | 4 | 1 |
| 3 |  D. Lainez |  Tigres UANL | 3 | 1 |
| 4 |  L. Herrera |  U.N.A.M. - Pumas | 3 | 1 |
| 5 |  N. Guzmán | Tigres UANL | 3 | 1 |
| 6 |  I. Tona |  Club Tijuana | 1 | 1 |
| 7 | J. Romaña | Leon | 5 | 0 |
| 8 | S. Barreto | CF Pachuca | 2 | 0 |
| 9 |  B. Méndez | Toluca | 4 | 0 |
| 10 | A. Cervantes | Club America | 6 | 0 |
| 11 | Juan José Guevara Possu | Leon | 6 | 0 |
| 12 | F. Pereira | Toluca | 6 | 0 |
| 13 | J. Rodríguez | Monterrey | 4 | 0 |
| 14 | W. Cartagena | Orlando City SC | 3 | 0 |
| 15 | R. Juárez | Club America | 3 | 0 |
| 16 | É. Sánchez | Club America | 6 | 0 |
| 17 | S. Vegas | Leon | 6 | 0 |
| 18 | L. Ocampos | Monterrey | 6 | 0 |
| 19 | D. Arcila | Leon | 6 | 0 |
| 20 | B. Šabović | Austin | 4 | 0 |